Assay Report Card

Basic Information

ID: ALA1804203

Type: Functional

Description: Vasorelaxant activity in Sprague-Dawley rat langendorff perfused thoracic aorta assessed as inhibition of phenylephrine-induced vasoconstriction at 10'-6 M relative to control

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Thoracic aorta

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
454.615.095.09
418.533.613.61
376.493.043.04
376.493.043.04
464.604.744.74
542.676.206.20
438.564.344.34
480.604.914.91
402.534.404.40
448.605.535.53
448.605.535.53
422.575.135.13
464.604.504.50
464.604.504.50
480.604.674.67
480.604.674.67
544.737.617.61
464.604.504.50
438.564.104.10