Basic Information
ID: ALA1804486
Type: Binding
Description: Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion at 50 uM after 5 mins by spectrophotometry
Format: BAO_0000357
Target: Protein-tyrosine phosphatase 2C(ALA3864)
Document: ALA1800013
Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion at 50 uM after 5 mins by spectrophotometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1804486
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.35 | 3.55 | 3.55 |
| 373.39 | 3.44 | 3.44 |
| 335.34 | 2.11 | 2.11 |
| 361.35 | 4.00 | 4.00 |
| 335.37 | 2.19 | 2.19 |
| 400.21 | 2.65 | 2.65 |
| 368.37 | 2.90 | 2.90 |
| 355.76 | 2.54 | 2.54 |
| 361.38 | 2.59 | 2.59 |
| 440.43 | 3.14 | 3.14 |
| 263.20 | 1.19 | 1.19 |
| 283.28 | 2.58 | 2.58 |
| 413.45 | 3.75 | 3.75 |
| 378.34 | -0.33 | -0.33 |
| 335.34 | 1.56 | 1.56 |
| 336.37 | 2.48 | 2.48 |
| 383.40 | 1.53 | 1.53 |
| 414.87 | 4.29 | 4.29 |
| 410.45 | 3.75 | 3.75 |
| 366.37 | 1.93 | 1.93 |
| 394.43 | 3.60 | 3.60 |
| 436.49 | 3.78 | 3.78 |
| 303.31 | 2.30 | 2.30 |
| 396.42 | 3.34 | 3.34 |
| 336.30 | 4.36 | 4.36 |
| 347.35 | 2.28 | 2.28 |
| 400.21 | 2.65 | 2.65 |
| 305.29 | 1.70 | 1.70 |
| 303.31 | 2.30 | 2.30 |
| 350.40 | 1.65 | 1.65 |
| 321.31 | 2.29 | 2.29 |
| 381.34 | 3.11 | 3.11 |
| 328.32 | 2.87 | 2.87 |
| 366.37 | 4.13 | 4.13 |
| 259.22 | 2.89 | 2.89 |