Basic Information
ID: ALA1804871
Type: Binding
Description: Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA1804871
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.42 | 2.35 | 2.35 |
| 436.53 | 4.62 | 4.62 |
| 411.48 | 3.50 | 3.50 |
| 411.48 | 3.50 | 3.50 |
| 455.49 | 4.02 | 4.02 |
| 411.48 | 3.50 | 3.50 |
| 445.93 | 4.16 | 4.16 |
| 455.54 | 3.82 | 3.82 |
| 379.42 | 3.09 | 3.09 |
| 378.43 | 3.12 | 3.12 |
| 409.51 | 4.19 | 4.19 |
| 422.49 | 3.16 | 3.16 |
| 439.54 | 4.15 | 4.15 |
| 409.51 | 4.19 | 4.19 |
| 433.46 | 4.81 | 4.81 |
| 383.45 | 3.93 | 3.93 |
| 399.90 | 4.45 | 4.45 |
| 449.45 | 4.69 | 4.69 |
| 423.54 | 4.58 | 4.58 |
| 429.93 | 4.46 | 4.46 |
| 474.38 | 4.57 | 4.57 |
| 413.47 | 3.94 | 3.94 |
| 429.93 | 4.46 | 4.46 |
| 474.38 | 4.57 | 4.57 |
| 425.51 | 3.81 | 3.81 |
| 420.49 | 3.67 | 3.67 |
| 474.38 | 4.57 | 4.57 |
| 429.93 | 4.46 | 4.46 |
| 413.47 | 3.94 | 3.94 |
| 420.49 | 3.67 | 3.67 |
| 474.38 | 4.57 | 4.57 |
| 362.41 | 1.74 | 1.74 |
| 444.43 | 3.85 | 3.85 |
| 390.46 | 2.96 | 2.96 |
| 395.48 | 3.80 | 3.80 |
| 365.46 | 3.79 | 3.79 |
| 365.46 | 3.79 | 3.79 |
| 395.48 | 3.80 | 3.80 |
| 399.90 | 4.45 | 4.45 |
| 383.45 | 3.93 | 3.93 |
| 444.35 | 4.56 | 4.56 |
| 379.49 | 4.10 | 4.10 |
| 390.47 | 3.67 | 3.67 |
| 433.46 | 4.81 | 4.81 |
| 467.44 | 4.99 | 4.99 |