Basic Information
ID: ALA1804897
Type: Binding
Description: Inhibition of recombinant HDAC8 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assay
Activity Charts
Bioactivity
Activity Types for Assay ALA1804897
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 292.32 | 1.88 | 1.88 |
| 290.34 | 2.47 | 2.47 |
| 303.39 | 1.94 | 1.94 |
| 317.37 | 2.42 | 2.42 |
| 301.37 | 2.72 | 2.72 |
| 331.40 | 2.73 | 2.73 |
| 315.40 | 3.03 | 3.03 |
| 301.37 | 3.33 | 3.33 |
| 301.30 | 1.71 | 1.71 |
| 300.31 | 2.32 | 2.32 |
| 289.36 | 2.74 | 2.74 |
| 319.39 | 2.27 | 2.27 |
| 260.32 | 2.47 | 2.47 |
| 331.40 | 2.45 | 2.45 |
| 379.44 | 3.72 | 3.72 |
| 316.43 | 3.76 | 3.76 |
| 294.76 | 3.12 | 3.12 |
| 276.32 | 2.17 | 2.17 |
| 318.35 | 2.24 | 2.24 |
| 315.35 | 1.96 | 1.96 |
| 266.35 | 2.53 | 2.53 |
| 214.25 | 0.76 | 0.76 |
| 198.25 | 1.17 | 1.17 |
| 240.33 | 2.20 | 2.20 |
| 270.31 | 1.11 | 1.11 |
| 331.44 | 2.72 | 2.72 |
| 359.50 | 3.50 | 3.50 |