Basic Information
ID: ALA1805099
Type: Binding
Description: Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting
Format: BAO_0000357
Organism: Rattus norvegicus
Target: Dual specificity tyrosine-phosphorylation-regulated kinase 1A(ALA5508)
Document: ALA1800025
Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1805099
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 245.24 | 0.54 | 0.54 |
| 288.31 | 0.13 | 0.13 |
| 337.34 | 2.36 | 2.36 |
| 351.32 | 2.08 | 2.08 |
| 365.35 | 2.13 | 2.13 |
| 307.31 | 2.35 | 2.35 |
| 259.26 | 0.80 | 0.80 |
| 273.29 | 1.19 | 1.19 |
| 287.32 | 1.58 | 1.58 |
| 287.32 | 1.58 | 1.58 |
| 301.35 | 1.97 | 1.97 |
| 301.35 | 1.83 | 1.83 |
| 315.37 | 2.22 | 2.22 |
| 285.30 | 1.36 | 1.36 |
| 299.33 | 1.58 | 1.58 |
| 313.36 | 2.12 | 2.12 |
| 289.29 | 0.17 | 0.17 |
| 303.32 | 0.82 | 0.82 |
| 303.32 | 0.56 | 0.56 |
| 331.37 | 1.34 | 1.34 |
| 358.40 | 0.51 | 0.51 |
| 287.28 | 0.72 | 0.72 |
| 345.31 | 0.26 | 0.26 |
| 335.36 | 2.37 | 2.37 |
| 379.37 | 2.10 | 2.10 |
| 321.34 | 2.70 | 2.70 |
| 337.34 | 2.40 | 2.40 |
| 351.36 | 2.70 | 2.70 |
| 365.35 | 2.42 | 2.42 |
| 379.37 | 2.47 | 2.47 |
| 259.31 | 1.56 | 1.56 |
| 322.21 | 2.62 | 2.62 |
| 273.29 | 1.24 | 1.24 |
| 315.37 | 2.36 | 2.36 |
| 349.39 | 3.16 | 3.16 |
| 259.26 | 0.85 | 0.85 |
| 285.30 | 1.24 | 1.24 |
| 321.34 | 2.66 | 2.66 |
| 323.31 | 2.06 | 2.06 |