Assay Report Card

Basic Information

ID: ALA1805479

Type: Functional

Description: Antibacterial activity against Escherichia coli UT189 infected in urinary tract infection C3H/HeN mouse model assessed as log reduction in bacterial count in kidney of mouse at 50 mg/kg, iv administered as single dose 1 hr before infection and measured after 3 hrs post infection

Organism: Escherichia coli

Strain: UT189

Tissue: Kidney

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
278.35-0.23-0.23
432.790.880.88
398.340.230.23