Basic Information
ID: ALA1805651
Type: Binding
Description: Inhibition of TNF-alpha-induced NFkappaB nuclear translocation in human A549 cells preincubated for 30 mins before TNFalpha challenge and measured 30 post TNFalpha challenge by fluorescence method
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Unchecked(ALA612545)
Document: ALA1799938
Inhibition of TNF-alpha-induced NFkappaB nuclear translocation in human A549 cells preincubated for 30 mins before TNFalpha challenge and measured 30 post TNFalpha challenge by fluorescence method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1805651
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.85 | 3.85 |
| 396.44 | 4.46 | 4.46 |
| 502.52 | 4.78 | 4.78 |
| 456.49 | 4.48 | 4.48 |
| 336.39 | 4.44 | 4.44 |
| 284.31 | 4.23 | 4.23 |
| 256.26 | 3.61 | 3.61 |
| 414.45 | 4.03 | 4.03 |
| 384.43 | 4.03 | 4.03 |
| 516.55 | 5.08 | 5.08 |
| 474.48 | 5.20 | 5.20 |
| 474.48 | 5.20 | 5.20 |
| 364.40 | 4.01 | 4.01 |
| 456.49 | 3.99 | 3.99 |
| 344.43 | 4.38 | 4.38 |
| 470.52 | 5.37 | 5.37 |
| 484.55 | 5.67 | 5.67 |
| 514.57 | 5.68 | 5.68 |
| 574.63 | 5.70 | 5.70 |
| 530.57 | 5.38 | 5.38 |
| 544.60 | 5.69 | 5.69 |
| 527.62 | 5.74 | 5.74 |
| 502.54 | 5.81 | 5.81 |
| 502.54 | 5.81 | 5.81 |
| 500.55 | 5.38 | 5.38 |
| 424.45 | 4.03 | 4.03 |
| 516.55 | 5.08 | 5.08 |
| 512.60 | 6.23 | 6.23 |
| 544.60 | 5.69 | 5.69 |
| 604.65 | 5.70 | 5.70 |
| 544.60 | 5.69 | 5.69 |
| 544.60 | 5.69 | 5.69 |
| 516.55 | 5.08 | 5.08 |
| 484.55 | 5.63 | 5.63 |
| 516.55 | 5.08 | 5.08 |
| 486.52 | 5.07 | 5.07 |
| 488.54 | 5.57 | 5.57 |
| 480.47 | 3.86 | 3.86 |