Assay Report Card

Basic Information

ID: ALA1805653

Type: Binding

Description: Inhibition of IKK in human A549 cells assessed as inhibition of TNF-alpha-induced IkappaB degradation at 0.5 to 25 uM preincubated for 4 hrs before TNFalpha challenge measured after 20 mins by Western blot analysis

Organism: Homo sapiens

Cell type: A549

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
530.575.385.38
502.545.815.81
516.555.085.08