Basic Information
ID: ALA1805653
Type: Binding
Description: Inhibition of IKK in human A549 cells assessed as inhibition of TNF-alpha-induced IkappaB degradation at 0.5 to 25 uM preincubated for 4 hrs before TNFalpha challenge measured after 20 mins by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Inhibitor of NF-kappa-B kinase (IKK)(ALA2111328)
Document: ALA1799938
Inhibition of IKK in human A549 cells assessed as inhibition of TNF-alpha-induced IkappaB degradation at 0.5 to 25 uM preincubated for 4 hrs before TNFalpha challenge measured after 20 mins by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1805653
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 530.57 | 5.38 | 5.38 |
| 502.54 | 5.81 | 5.81 |
| 516.55 | 5.08 | 5.08 |