Basic Information
ID: ALA1805669
Type: Functional
Description: Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-MSH challenge measured after 40 mins
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1805669
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 560.13 | 6.43 | 6.43 |
| 600.19 | 6.70 | 6.70 |
| 600.19 | 6.70 | 6.70 |
| 614.22 | 7.05 | 7.05 |
| 614.22 | 7.05 | 7.05 |
| 614.22 | 6.90 | 6.90 |
| 614.22 | 6.90 | 6.90 |
| 600.19 | 6.56 | 6.56 |
| 600.19 | 6.56 | 6.56 |
| 614.22 | 6.95 | 6.95 |
| 614.22 | 6.95 | 6.95 |
| 626.23 | 7.09 | 7.09 |
| 626.23 | 7.09 | 7.09 |
| 628.25 | 7.34 | 7.34 |
| 642.28 | 7.73 | 7.73 |
| 642.28 | 7.59 | 7.59 |
| 676.29 | 8.13 | 8.13 |
| 632.21 | 6.90 | 6.90 |
| 668.19 | 7.49 | 7.49 |
| 668.19 | 7.49 | 7.49 |
| 630.22 | 5.92 | 5.92 |
| 670.28 | 7.11 | 7.11 |
| 658.27 | 6.70 | 6.70 |
| 628.25 | 7.29 | 7.29 |
| 642.27 | 7.68 | 7.68 |
| 626.23 | 7.05 | 7.05 |
| 662.21 | 7.29 | 7.29 |
| 656.26 | 6.67 | 6.67 |
| 668.27 | 6.81 | 6.81 |
| 640.26 | 7.44 | 7.44 |
| 658.25 | 7.38 | 7.38 |
| 658.25 | 7.38 | 7.38 |
| 676.24 | 7.68 | 7.68 |
| 656.26 | 6.41 | 6.41 |
| 656.26 | 6.41 | 6.41 |
| 670.28 | 7.06 | 7.06 |
| 670.28 | 7.06 | 7.06 |