Basic Information
ID: ALA1805773
Type: Binding
Description: Inhibition of Nampt activity in H2O2-induced DNA damage in human MCF10A cells stably transfected with PIK3CA (H1047R) assessed as loss of PARP activity
Organism: Homo sapiens
Cell type: MCF-10A
Activity Charts
Bioactivity
Activity Types for Assay ALA1805773
INH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.12 | 3.30 | 3.30 |
| 486.52 | 4.09 | 4.09 |
| 504.51 | 4.23 | 4.23 |
| 484.99 | 4.47 | 4.47 |
| 486.52 | 4.09 | 4.09 |
| 468.53 | 3.95 | 3.95 |
| 481.60 | 4.54 | 4.54 |
| 520.64 | 5.02 | 5.02 |
| 365.86 | 4.30 | 4.30 |
| 379.89 | 4.69 | 4.69 |
| 393.92 | 5.08 | 5.08 |
| 407.95 | 5.47 | 5.47 |
| 407.95 | 5.33 | 5.33 |
| 421.97 | 5.72 | 5.72 |
| 389.89 | 4.30 | 4.30 |
| 405.93 | 5.08 | 5.08 |
| 419.96 | 5.64 | 5.64 |
| 405.93 | 5.25 | 5.25 |
| 441.96 | 5.87 | 5.87 |
| 437.50 | 2.90 | 2.90 |
| 467.57 | 4.23 | 4.23 |
| 502.02 | 4.88 | 4.88 |
| 487.99 | 4.33 | 4.33 |
| 490.95 | 2.40 | 2.40 |
| 485.98 | 3.94 | 3.94 |
| 516.00 | 4.41 | 4.41 |
| 522.61 | 4.38 | 4.38 |
| 467.57 | 4.15 | 4.15 |
| 465.56 | 3.60 | 3.60 |
| 467.57 | 3.98 | 3.98 |
| 481.56 | 3.51 | 3.51 |
| 495.58 | 4.07 | 4.07 |
| 447.88 | 3.16 | 3.16 |
| 433.90 | 3.52 | 3.52 |
| 501.97 | 3.04 | 3.04 |
| 627.19 | 3.02 | 3.02 |
| 503.01 | 4.28 | 4.28 |
| 406.47 | 2.62 | 2.62 |
| 405.49 | 2.91 | 2.91 |
| 419.51 | 2.95 | 2.95 |
| 427.47 | 2.35 | 2.35 |
| 387.45 | 2.23 | 2.23 |
| 418.46 | 1.99 | 1.99 |
| 403.44 | 1.60 | 1.60 |
| 525.01 | 4.34 | 4.34 |
| 485.98 | 3.86 | 3.86 |
| 516.05 | 5.19 | 5.19 |
| 555.08 | 5.67 | 5.67 |
| 451.53 | 3.21 | 3.21 |
| 490.57 | 3.69 | 3.69 |
| 457.58 | 2.61 | 2.61 |
| 494.55 | 3.54 | 3.54 |
| 468.53 | 3.95 | 3.95 |