Basic Information
ID: ALA1806090
Type: Binding
Description: Inhibition of human MMP14 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1806090
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.55 | 2.58 | 2.58 |
| 445.42 | 3.33 | 3.33 |
| 518.51 | 3.14 | 3.14 |
| 411.86 | 2.96 | 2.96 |
| 411.86 | 2.96 | 2.96 |
| 446.31 | 3.61 | 3.61 |
| 393.42 | 2.01 | 2.01 |
| 435.50 | 3.09 | 3.09 |
| 453.52 | 3.97 | 3.97 |
| 445.42 | 3.33 | 3.33 |
| 461.41 | 3.21 | 3.21 |
| 423.51 | 3.03 | 3.03 |
| 477.48 | 3.92 | 3.92 |
| 497.57 | 3.20 | 3.20 |
| 551.54 | 4.09 | 4.09 |
| 532.54 | 3.53 | 3.53 |
| 502.47 | 3.04 | 3.04 |
| 498.48 | 3.12 | 3.12 |
| 474.46 | 3.12 | 3.12 |
| 502.51 | 3.90 | 3.90 |
| 460.55 | 3.15 | 3.15 |
| 456.56 | 3.35 | 3.35 |
| 460.60 | 4.12 | 4.12 |
| 492.59 | 3.03 | 3.03 |
| 474.58 | 3.54 | 3.54 |
| 492.58 | 1.63 | 1.63 |
| 420.44 | 1.61 | 1.61 |
| 458.49 | 1.95 | 1.95 |
| 478.52 | 1.97 | 1.97 |
| 460.51 | 2.48 | 2.48 |
| 474.54 | 2.53 | 2.53 |
| 484.50 | 3.77 | 3.77 |
| 444.43 | 2.90 | 2.90 |
| 557.59 | 2.94 | 2.94 |
| 486.51 | 4.02 | 4.02 |
| 472.49 | 3.63 | 3.63 |
| 534.58 | 3.85 | 3.85 |
| 460.43 | 2.78 | 2.78 |
| 500.50 | 3.65 | 3.65 |
| 551.54 | 4.09 | 4.09 |