Basic Information
ID: ALA1809501
Type: Binding
Description: Agonist activity at human FLAG-tagged SXR ligand binding domain expressed in human HepG2 cells co-transfected with pGVP2-Gal4 vector assessed as induction of CYP3A4 gene expression at 5 x 10'-6 M after 48 hrs by dual-luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA1809501
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.54 | 7.19 | 7.19 |
| 308.42 | 5.46 | 5.46 |
| 444.66 | 8.92 | 8.92 |
| 450.71 | 9.16 | 9.16 |
| 294.39 | 5.07 | 5.07 |
| 240.30 | 3.74 | 3.74 |
| 715.20 | 15.91 | 15.91 |
| 430.63 | 8.53 | 8.53 |
| 566.87 | 11.98 | 11.98 |
| 703.11 | 15.43 | 15.43 |