Basic Information
ID: ALA1810043
Type: Binding
Description: Displacement of [125I]-PA cyclopamine from smoothened expressed in african green monkey COS-1 cells after 10 mins by autoradiography
Cell type: COS-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1810043
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.57 | 4.45 | 4.45 |
| 457.49 | 3.38 | 3.38 |
| 467.53 | 3.79 | 3.79 |
| 467.53 | 3.79 | 3.79 |
| 501.97 | 4.44 | 4.44 |
| 501.97 | 4.44 | 4.44 |
| 501.97 | 4.44 | 4.44 |
| 535.53 | 4.80 | 4.80 |
| 497.56 | 3.79 | 3.79 |
| 473.56 | 3.85 | 3.85 |
| 471.52 | 2.52 | 2.52 |
| 456.51 | 2.91 | 2.91 |
| 458.52 | 5.76 | 5.76 |
| 452.56 | 4.86 | 4.86 |
| 470.53 | 3.30 | 3.30 |
| 470.53 | 2.32 | 2.32 |
| 329.36 | 1.26 | 1.26 |
| 313.36 | 1.04 | 1.04 |
| 381.48 | 2.60 | 2.60 |
| 355.44 | 2.06 | 2.06 |
| 367.49 | 3.07 | 3.07 |
| 342.40 | 1.17 | 1.17 |
| 394.43 | 1.99 | 1.99 |
| 396.49 | 2.53 | 2.53 |
| 398.51 | 2.78 | 2.78 |
| 426.56 | 3.51 | 3.51 |
| 459.33 | 4.03 | 4.03 |
| 459.33 | 4.03 | 4.03 |
| 459.33 | 4.03 | 4.03 |
| 442.88 | 3.52 | 3.52 |
| 434.45 | 2.45 | 2.45 |
| 466.54 | 4.39 | 4.39 |
| 480.57 | 4.41 | 4.41 |
| 466.54 | 4.39 | 4.39 |
| 466.54 | 4.39 | 4.39 |
| 454.53 | 4.08 | 4.08 |
| 440.50 | 4.03 | 4.03 |
| 476.54 | 5.19 | 5.19 |
| 502.57 | 5.71 | 5.71 |
| 406.49 | 3.63 | 3.63 |
| 458.56 | 4.56 | 4.56 |
| 480.57 | 4.78 | 4.78 |
| 466.54 | 4.00 | 4.00 |
| 482.92 | 3.16 | 3.16 |
| 438.92 | 3.68 | 3.68 |
| 438.92 | 3.68 | 3.68 |
| 477.32 | 4.17 | 4.17 |
| 477.32 | 4.17 | 4.17 |
| 543.33 | 4.93 | 4.93 |
| 527.33 | 5.05 | 5.05 |
| 537.43 | 3.43 | 3.43 |
| 484.34 | 3.90 | 3.90 |
| 463.93 | 3.56 | 3.56 |
| 432.52 | 3.85 | 3.85 |
| 458.44 | 3.74 | 3.74 |
| 415.45 | 2.59 | 2.59 |
| 420.47 | 2.73 | 2.73 |