Basic Information
ID: ALA1810320
Type: Functional
Description: Antagonist activity at human CXCR3 expressed in mouse L1.2 cells assessed as inhibition of ITAC-induced calcium mobilization by FLIPR assay
Organism: Homo sapiens
Cell type: L1.2
Activity Charts
Bioactivity
Activity Types for Assay ALA1810320
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.54 | 4.51 | 4.51 |
| 372.43 | 3.13 | 3.13 |
| 400.48 | 3.78 | 3.78 |
| 400.48 | 3.73 | 3.73 |
| 488.59 | 3.76 | 3.76 |
| 430.51 | 3.09 | 3.09 |
| 412.49 | 3.87 | 3.87 |
| 426.52 | 4.26 | 4.26 |
| 440.55 | 4.65 | 4.65 |
| 454.57 | 5.04 | 5.04 |
| 424.50 | 4.04 | 4.04 |
| 438.53 | 4.78 | 4.78 |
| 441.54 | 3.07 | 3.07 |
| 455.52 | 2.60 | 2.60 |
| 455.56 | 3.41 | 3.41 |
| 483.57 | 3.33 | 3.33 |
| 442.52 | 3.50 | 3.50 |
| 470.57 | 4.28 | 4.28 |
| 490.59 | 2.90 | 2.90 |
| 456.55 | 3.62 | 3.62 |
| 472.55 | 2.59 | 2.59 |
| 442.52 | 3.23 | 3.23 |
| 442.52 | 3.23 | 3.23 |
| 444.51 | 4.40 | 4.40 |
| 444.51 | 4.40 | 4.40 |
| 444.51 | 4.40 | 4.40 |
| 456.55 | 4.27 | 4.27 |
| 456.55 | 4.27 | 4.27 |
| 456.55 | 4.27 | 4.27 |
| 483.62 | 4.32 | 4.32 |
| 483.62 | 4.32 | 4.32 |
| 483.62 | 4.32 | 4.32 |
| 432.55 | 4.32 | 4.32 |
| 432.55 | 4.32 | 4.32 |
| 415.50 | 3.59 | 3.59 |
| 418.54 | 3.68 | 3.68 |
| 432.57 | 4.07 | 4.07 |
| 446.60 | 4.46 | 4.46 |
| 448.57 | 3.04 | 3.04 |
| 364.45 | 2.37 | 2.37 |
| 435.57 | 2.69 | 2.69 |
| 440.55 | 3.94 | 3.94 |
| 430.51 | 3.53 | 3.53 |
| 411.51 | 3.87 | 3.87 |
| 425.53 | 3.80 | 3.80 |
| 526.64 | 4.69 | 4.69 |
| 470.57 | 3.73 | 3.73 |
| 497.64 | 4.30 | 4.30 |
| 523.68 | 4.83 | 4.83 |
| 537.71 | 5.22 | 5.22 |
| 552.72 | 3.98 | 3.98 |
| 539.68 | 4.07 | 4.07 |