Basic Information
ID: ALA1811085
Type: Binding
Description: Inhibition of RET kinase
Activity Charts
Bioactivity
Activity Types for Assay ALA1811085
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.40 | 4.01 | 4.01 |
| 345.41 | 3.61 | 3.61 |
| 305.32 | 3.90 | 3.90 |
| 355.32 | 4.78 | 4.78 |
| 315.38 | 4.33 | 4.33 |
| 301.35 | 4.07 | 4.07 |
| 301.35 | 4.07 | 4.07 |
| 303.32 | 3.47 | 3.47 |
| 297.32 | 2.62 | 2.62 |
| 341.35 | 3.32 | 3.32 |
| 386.43 | 3.08 | 3.08 |
| 373.39 | 3.17 | 3.17 |
| 431.45 | 4.55 | 4.55 |
| 356.39 | 3.71 | 3.71 |
| 447.55 | 5.56 | 5.56 |
| 460.55 | 4.47 | 4.47 |
| 447.50 | 4.55 | 4.55 |
| 447.50 | 4.85 | 4.85 |
| 461.53 | 5.20 | 5.20 |
| 467.58 | 3.42 | 3.42 |
| 405.41 | 3.95 | 3.95 |
| 387.42 | 3.81 | 3.81 |
| 413.49 | 3.77 | 3.77 |
| 440.60 | 4.94 | 4.94 |
| 464.83 | 5.55 | 5.55 |
| 413.49 | 4.07 | 4.07 |
| 497.61 | 3.05 | 3.05 |
| 481.61 | 3.81 | 3.81 |
| 386.50 | 4.65 | 4.65 |
| 503.57 | 4.75 | 4.75 |
| 316.37 | 3.65 | 3.65 |
| 403.39 | 3.21 | 3.21 |
| 427.48 | 2.43 | 2.43 |
| 427.56 | 3.86 | 3.86 |
| 451.56 | 6.24 | 6.24 |
| 495.55 | 6.28 | 6.28 |
| 294.36 | 1.95 | 1.95 |
| 308.39 | 2.70 | 2.70 |
| 309.37 | 2.74 | 2.74 |
| 305.39 | 3.62 | 3.62 |
| 490.57 | 4.35 | 4.35 |
| 323.40 | 3.39 | 3.39 |
| 356.22 | 5.07 | 5.07 |
| 427.51 | 4.46 | 4.46 |
| 338.36 | 2.77 | 2.77 |
| 467.58 | 3.38 | 3.38 |
| 338.36 | 2.77 | 2.77 |
| 453.55 | 3.03 | 3.03 |
| 377.40 | 3.79 | 3.79 |
| 395.43 | 4.19 | 4.19 |
| 385.43 | 3.29 | 3.29 |
| 348.79 | 3.01 | 3.01 |
| 435.39 | 3.60 | 3.60 |
| 481.61 | 3.81 | 3.81 |
| 493.62 | 3.91 | 3.91 |
| 358.45 | 3.92 | 3.92 |
| 358.45 | 3.87 | 3.87 |
| 384.49 | 4.40 | 4.40 |
| 413.53 | 3.55 | 3.55 |
| 445.49 | 4.61 | 4.61 |
| 412.30 | 3.02 | 3.02 |
| 372.48 | 4.18 | 4.18 |
| 461.53 | 5.24 | 5.24 |
| 308.39 | 2.53 | 2.53 |
| 344.42 | 3.53 | 3.53 |
| 344.38 | 3.64 | 3.64 |
| 455.52 | 3.54 | 3.54 |
| 426.50 | 4.01 | 4.01 |
| 260.25 | 1.54 | 1.54 |
| 295.35 | 2.61 | 2.61 |
| 279.35 | 3.37 | 3.37 |
| 358.20 | 3.41 | 3.41 |
| 330.33 | 3.70 | 3.70 |