Basic Information
ID: ALA1811278
Type: Functional
Description: Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha production treated 30 mins before LPS challenge measured after 6 hrs by ELISA
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA1811278
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.48 | 4.89 | 4.89 |
| 564.62 | 5.55 | 5.55 |
| 385.43 | 3.42 | 3.42 |
| 399.45 | 3.68 | 3.68 |
| 413.48 | 4.07 | 4.07 |
| 427.51 | 4.46 | 4.46 |
| 425.49 | 4.21 | 4.21 |
| 452.47 | 4.56 | 4.56 |
| 443.46 | 3.82 | 3.82 |
| 349.39 | 2.79 | 2.79 |
| 391.48 | 3.96 | 3.96 |
| 387.44 | 3.19 | 3.19 |
| 413.48 | 3.99 | 3.99 |
| 429.48 | 3.69 | 3.69 |
| 429.48 | 3.69 | 3.69 |
| 417.44 | 3.82 | 3.82 |
| 443.46 | 3.41 | 3.41 |
| 414.47 | 3.38 | 3.38 |
| 440.51 | 3.92 | 3.92 |
| 426.48 | 3.61 | 3.61 |
| 426.48 | 3.61 | 3.61 |
| 477.53 | 4.16 | 4.16 |
| 414.47 | 3.54 | 3.54 |
| 414.47 | 3.54 | 3.54 |
| 428.50 | 3.55 | 3.55 |
| 428.50 | 3.55 | 3.55 |
| 415.45 | 3.81 | 3.81 |
| 464.53 | 4.69 | 4.69 |
| 478.56 | 4.70 | 4.70 |
| 478.56 | 4.70 | 4.70 |