Basic Information
ID: ALA1811532
Type: Binding
Description: Inhibition of B-Raf V600E mutant in human SK-MEL-28 cells assessed as reduction of ERK phosphorylation after 1 hr
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA1811532
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 624.09 | 6.72 | 6.72 |
| 602.65 | 7.11 | 7.11 |
| 624.10 | 6.72 | 6.72 |
| 587.71 | 5.99 | 5.99 |
| 596.71 | 7.65 | 7.65 |
| 596.78 | 6.92 | 6.92 |
| 654.82 | 6.00 | 6.00 |
| 654.82 | 5.46 | 5.46 |
| 639.81 | 5.61 | 5.61 |
| 672.81 | 6.14 | 6.14 |
| 672.81 | 6.14 | 6.14 |
| 672.81 | 6.14 | 6.14 |
| 689.27 | 6.65 | 6.65 |
| 690.80 | 6.28 | 6.28 |
| 690.80 | 6.28 | 6.28 |
| 649.75 | 6.44 | 6.44 |
| 667.74 | 6.58 | 6.58 |
| 667.74 | 6.58 | 6.58 |
| 667.74 | 6.58 | 6.58 |