Basic Information
ID: ALA1811699
Type: Binding
Description: Inhibition of human SGLT1 expressed in human 293 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake after 1.5 hrs by scintillation counting in presence of 25 % human plasma
Organism: Homo sapiens
Tissue: Plasma
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1811699
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 380.82 | 1.15 | 1.15 |
| 424.88 | 0.82 | 0.82 |
| 478.97 | 2.39 | 2.39 |
| 462.93 | 1.47 | 1.47 |
| 432.90 | 1.85 | 1.85 |
| 458.94 | 2.24 | 2.24 |
| 466.91 | 1.39 | 1.39 |
| 438.86 | 0.91 | 0.91 |
| 390.86 | 2.09 | 2.09 |
| 388.85 | 1.43 | 1.43 |
| 407.85 | 0.54 | 0.54 |
| 389.84 | 1.32 | 1.32 |
| 404.89 | 2.32 | 2.32 |
| 420.89 | 1.43 | 1.43 |
| 448.94 | 2.12 | 2.12 |
| 475.97 | 1.96 | 1.96 |
| 444.91 | 2.61 | 2.61 |
| 464.94 | 2.03 | 2.03 |
| 476.95 | 1.86 | 1.86 |
| 464.94 | 2.00 | 2.00 |
| 478.97 | 2.39 | 2.39 |
| 493.00 | 2.78 | 2.78 |
| 507.02 | 3.17 | 3.17 |
| 494.97 | 1.63 | 1.63 |
| 434.92 | 2.12 | 2.12 |
| 448.94 | 2.17 | 2.17 |