Basic Information
ID: ALA1811701
Type: Binding
Description: Inhibition of human SGLT2 expressed in human 293 cells assessed as inhibition of [14C]-methyl-alpha-D-glucopyranoside uptake at 10 nM after 1.5 hrs by scintillation counting in presence of 25 % human plasma
Organism: Homo sapiens
Tissue: Plasma
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1811701
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.88 | 2.01 | 2.01 |
| 432.90 | 1.85 | 1.85 |
| 466.91 | 1.39 | 1.39 |
| 407.85 | 0.54 | 0.54 |
| 448.94 | 2.12 | 2.12 |
| 475.97 | 1.96 | 1.96 |
| 444.91 | 2.61 | 2.61 |
| 476.95 | 1.86 | 1.86 |
| 507.02 | 3.17 | 3.17 |
| 494.97 | 1.63 | 1.63 |
| 434.92 | 2.12 | 2.12 |
| 448.94 | 2.17 | 2.17 |