Basic Information
ID: ALA1816318
Type: Functional
Description: Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene expression
Cell type: Shh Light II
Activity Charts
Bioactivity
Activity Types for Assay ALA1816318
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.39 | 4.39 |
| 466.54 | 4.39 | 4.39 |
| 459.33 | 4.03 | 4.03 |
| 459.33 | 4.03 | 4.03 |
| 459.33 | 4.03 | 4.03 |
| 459.33 | 4.03 | 4.03 |
| 477.32 | 4.17 | 4.17 |
| 484.34 | 3.90 | 3.90 |
| 530.41 | 3.73 | 3.73 |
| 537.43 | 3.43 | 3.43 |
| 467.53 | 3.79 | 3.79 |
| 501.97 | 4.44 | 4.44 |
| 492.54 | 3.66 | 3.66 |
| 473.56 | 3.85 | 3.85 |
| 456.51 | 2.91 | 2.91 |
| 490.95 | 3.56 | 3.56 |
| 474.50 | 3.05 | 3.05 |
| 480.57 | 4.78 | 4.78 |
| 480.57 | 4.78 | 4.78 |
| 470.53 | 3.30 | 3.30 |