Basic Information
ID: ALA1816726
Type: Binding
Description: Inhibition of 17Beta-HSD3 expressed in homogenized HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in presence of NADPH at 0.1 uM
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1816726
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.67 | 5.85 | 5.85 |
| 423.64 | 5.46 | 5.46 |
| 375.60 | 4.67 | 4.67 |
| 431.71 | 6.23 | 6.23 |
| 387.61 | 4.82 | 4.82 |
| 477.73 | 6.28 | 6.28 |
| 470.74 | 5.28 | 5.28 |
| 402.62 | 3.58 | 3.58 |
| 464.69 | 5.15 | 5.15 |
| 478.72 | 5.15 | 5.15 |
| 546.72 | 6.17 | 6.17 |
| 546.72 | 6.17 | 6.17 |
| 546.72 | 6.17 | 6.17 |
| 578.79 | 6.76 | 6.76 |
| 513.17 | 5.80 | 5.80 |
| 508.75 | 5.16 | 5.16 |
| 479.71 | 4.54 | 4.54 |
| 614.72 | 7.18 | 7.18 |
| 614.72 | 7.18 | 7.18 |
| 614.72 | 7.18 | 7.18 |
| 574.77 | 6.94 | 6.94 |
| 574.77 | 6.94 | 6.94 |
| 574.77 | 6.94 | 6.94 |
| 606.84 | 7.54 | 7.54 |
| 541.22 | 6.58 | 6.58 |
| 536.80 | 5.93 | 5.93 |
| 507.76 | 5.32 | 5.32 |
| 642.77 | 7.96 | 7.96 |
| 642.77 | 7.96 | 7.96 |
| 642.77 | 7.96 | 7.96 |
| 492.70 | 4.79 | 4.79 |
| 498.75 | 5.05 | 5.05 |
| 560.70 | 5.81 | 5.81 |
| 560.70 | 5.81 | 5.81 |
| 560.70 | 5.81 | 5.81 |
| 520.76 | 5.56 | 5.56 |
| 526.81 | 5.83 | 5.83 |
| 588.76 | 6.58 | 6.58 |
| 588.76 | 6.58 | 6.58 |
| 596.76 | 5.35 | 5.35 |
| 596.76 | 5.35 | 5.35 |
| 596.76 | 5.35 | 5.35 |
| 624.81 | 6.13 | 6.13 |
| 624.81 | 6.13 | 6.13 |
| 624.81 | 6.13 | 6.13 |
| 626.88 | 6.39 | 6.39 |
| 435.61 | 5.99 | 5.99 |
| 449.64 | 6.30 | 6.30 |
| 465.63 | 6.00 | 6.00 |
| 503.61 | 7.01 | 7.01 |
| 504.59 | 6.40 | 6.40 |
| 503.61 | 7.01 | 7.01 |
| 503.61 | 7.01 | 7.01 |
| 571.60 | 8.03 | 8.03 |
| 427.63 | 6.12 | 6.12 |
| 477.69 | 6.93 | 6.93 |
| 389.54 | 3.78 | 3.78 |
| 452.43 | 5.18 | 5.18 |
| 479.66 | 6.18 | 6.18 |
| 527.73 | 5.57 | 5.57 |
| 456.67 | 5.28 | 5.28 |
| 506.73 | 6.31 | 6.31 |
| 498.75 | 6.44 | 6.44 |
| 472.71 | 5.91 | 5.91 |
| 486.70 | 5.44 | 5.44 |