Basic Information
ID: ALA1817162
Type: Binding
Description: Inhibition of HCV genotype 1b J4 N-terminal His-tagged NS5Bdelta21 polymerase expressed in Escherichia coli C41(DE3) assessed as amount of double-stranded RNA synthesis
Organism: Hepatitis C virus isolate HC-J4
Activity Charts
Bioactivity
Activity Types for Assay ALA1817162
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 254.24 | 2.71 | 2.71 |
| 282.30 | 3.28 | 3.28 |
| 270.24 | 2.42 | 2.42 |
| 254.24 | 2.71 | 2.71 |
| 266.30 | 3.57 | 3.57 |
| 254.24 | 2.71 | 2.71 |
| 270.24 | 2.42 | 2.42 |
| 286.24 | 2.13 | 2.13 |
| 298.29 | 3.03 | 3.03 |
| 298.29 | 3.03 | 3.03 |
| 254.24 | 2.71 | 2.71 |
| 254.24 | 2.71 | 2.71 |
| 254.24 | 2.71 | 2.71 |
| 298.29 | 3.03 | 3.03 |
| 338.40 | 4.66 | 4.66 |
| 254.24 | 2.71 | 2.71 |
| 254.24 | 2.71 | 2.71 |
| 238.24 | 3.01 | 3.01 |
| 270.24 | 2.42 | 2.42 |
| 266.30 | 3.63 | 3.63 |
| 298.29 | 3.03 | 3.03 |
| 298.29 | 3.03 | 3.03 |
| 328.32 | 3.03 | 3.03 |
| 280.32 | 4.13 | 4.13 |
| 294.35 | 4.35 | 4.35 |
| 294.35 | 4.31 | 4.31 |
| 336.39 | 2.76 | 2.76 |
| 256.23 | 3.15 | 3.15 |
| 286.24 | 2.13 | 2.13 |
| 314.29 | 2.73 | 2.73 |
| 344.32 | 2.74 | 2.74 |
| 296.32 | 3.84 | 3.84 |
| 310.35 | 4.06 | 4.06 |
| 336.39 | 4.76 | 4.76 |
| 339.35 | 2.55 | 2.55 |
| 272.23 | 2.85 | 2.85 |
| 310.35 | 3.94 | 3.94 |
| 364.44 | 5.37 | 5.37 |
| 278.35 | 4.65 | 4.65 |
| 314.33 | 4.92 | 4.92 |
| 276.21 | 3.72 | 3.72 |
| 516.64 | 8.51 | 8.51 |
| 349.39 | 4.47 | 4.47 |