Assay Report Card

Basic Information

ID: ALA1817163

Type: Binding

Description: Inhibition of HCV genotype 1b J4 N-terminal His-tagged NS5Bdelta21 polymerase expressed in Escherichia coli C41(DE3) assessed as amount of double-stranded RNA synthesis at 20 uM

Organism: Hepatitis C virus isolate HC-J4

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
254.242.712.71
282.303.283.28
270.242.422.42
254.242.712.71
266.303.573.57
254.242.712.71
270.242.422.42
286.242.132.13
298.293.033.03
298.293.033.03
254.242.712.71
254.242.712.71
254.242.712.71
298.293.033.03
338.404.664.66
254.242.712.71
254.242.712.71
238.243.013.01
270.242.422.42
266.303.633.63
298.293.033.03
298.293.033.03
328.323.033.03
280.324.134.13
294.354.354.35
294.354.314.31
336.392.762.76
256.233.153.15
286.242.132.13
314.292.732.73
344.322.742.74
296.323.843.84
310.354.064.06
336.394.764.76
339.352.552.55
272.232.852.85
310.353.943.94
364.445.375.37
278.354.654.65
314.334.924.92
276.213.723.72
516.648.518.51
349.394.474.47