Basic Information
ID: ALA1817224
Type: Binding
Description: Binding affinity to CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as increase in iodine influx measured as YFP quenching rate after 24 hrs by fluorescence assay
Format: BAO_0000219
Cell type: FRT
Target: Unchecked(ALA612545)
Document: ALA1811821
Binding affinity to CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as increase in iodine influx measured as YFP quenching rate after 24 hrs by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1817224
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 346.34 | 2.18 | 2.18 |
| 409.90 | 3.25 | 3.25 |
| 395.87 | 2.94 | 2.94 |
| 429.42 | 3.30 | 3.30 |
| 416.29 | 3.28 | 3.28 |
| 395.87 | 2.94 | 2.94 |
| 453.52 | 3.65 | 3.65 |
| 507.49 | 4.54 | 4.54 |
| 491.49 | 4.66 | 4.66 |
| 415.39 | 3.00 | 3.00 |
| 443.45 | 3.78 | 3.78 |
| 491.49 | 4.66 | 4.66 |
| 519.55 | 5.44 | 5.44 |
| 571.62 | 6.39 | 6.39 |
| 507.49 | 4.54 | 4.54 |
| 559.57 | 5.65 | 5.65 |
| 465.58 | 4.73 | 4.73 |
| 423.92 | 3.72 | 3.72 |
| 554.88 | 6.38 | 6.38 |
| 421.49 | 4.84 | 4.84 |
| 409.53 | 4.68 | 4.68 |
| 409.48 | 3.93 | 3.93 |