Basic Information
ID: ALA1817226
Type: Binding
Description: Activity at CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as maximal increase in iodine influx measured as YFP quenching rate up to 20 uM after 24 hrs by fluorescence assay
Cell type: FRT
Activity Charts
Bioactivity
Activity Types for Assay ALA1817226
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.60 | 4.22 | 4.22 |
| 497.57 | 3.97 | 3.97 |
| 375.45 | 2.59 | 2.59 |
| 395.87 | 2.94 | 2.94 |
| 562.99 | 4.22 | 4.22 |
| 517.99 | 4.31 | 4.31 |
| 528.54 | 3.57 | 3.57 |
| 528.54 | 3.57 | 3.57 |
| 483.55 | 3.66 | 3.66 |
| 453.52 | 3.65 | 3.65 |
| 507.49 | 4.54 | 4.54 |
| 425.51 | 3.24 | 3.24 |
| 535.62 | 4.77 | 4.77 |
| 548.02 | 4.32 | 4.32 |