Basic Information
ID: ALA1817227
Type: Binding
Description: Activity at CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as maximal increase in iodine influx measured as YFP quenching rate at 0.2 uM after 24 hrs by fluorescence assay
Cell type: FRT
Activity Charts
Bioactivity
Activity Types for Assay ALA1817227
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 511.60 | 4.22 | 4.22 |
| 409.90 | 3.25 | 3.25 |
| 395.87 | 2.94 | 2.94 |
| 497.57 | 3.97 | 3.97 |
| 429.42 | 3.30 | 3.30 |
| 375.45 | 2.59 | 2.59 |
| 395.87 | 2.94 | 2.94 |
| 562.99 | 4.22 | 4.22 |
| 517.99 | 4.31 | 4.31 |
| 416.29 | 3.28 | 3.28 |
| 528.54 | 3.57 | 3.57 |
| 395.87 | 2.94 | 2.94 |
| 528.54 | 3.57 | 3.57 |
| 483.55 | 3.66 | 3.66 |
| 453.52 | 3.65 | 3.65 |
| 453.52 | 3.65 | 3.65 |
| 507.49 | 4.54 | 4.54 |
| 507.49 | 4.54 | 4.54 |
| 491.49 | 4.66 | 4.66 |
| 415.39 | 3.00 | 3.00 |
| 443.45 | 3.78 | 3.78 |
| 491.49 | 4.66 | 4.66 |
| 519.55 | 5.44 | 5.44 |
| 571.62 | 6.39 | 6.39 |
| 507.49 | 4.54 | 4.54 |
| 559.57 | 5.65 | 5.65 |
| 465.58 | 4.73 | 4.73 |
| 425.51 | 3.24 | 3.24 |
| 535.62 | 4.77 | 4.77 |
| 423.92 | 3.72 | 3.72 |
| 554.88 | 6.38 | 6.38 |
| 548.02 | 4.32 | 4.32 |