Basic Information
ID: ALA1817446
Type: Binding
Description: Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs by HPLC analysis
Organism: Mus musculus
Cell type: P815B
Activity Charts
Bioactivity
Activity Types for Assay ALA1817446
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.16 | 2.04 | 2.04 |
| 238.26 | 3.87 | 3.87 |
| 238.26 | 3.87 | 3.87 |
| 238.26 | 3.87 | 3.87 |
| 220.28 | 3.73 | 3.73 |
| 220.28 | 3.73 | 3.73 |
| 220.28 | 3.73 | 3.73 |
| 202.28 | 2.92 | 2.92 |
| 187.20 | 2.27 | 2.27 |
| 220.28 | 3.73 | 3.73 |
| 270.33 | 4.89 | 4.89 |
| 221.26 | 3.13 | 3.13 |
| 221.26 | 3.13 | 3.13 |
| 221.26 | 3.13 | 3.13 |
| 171.20 | 1.98 | 1.98 |
| 265.29 | 3.78 | 3.78 |
| 231.30 | 4.41 | 4.41 |
| 252.29 | 3.88 | 3.88 |
| 234.30 | 4.04 | 4.04 |
| 296.37 | 5.40 | 5.40 |
| 238.26 | 3.87 | 3.87 |
| 254.72 | 4.39 | 4.39 |
| 299.17 | 4.50 | 4.50 |
| 245.28 | 3.60 | 3.60 |
| 265.27 | 3.64 | 3.64 |
| 278.31 | 3.52 | 3.52 |
| 254.72 | 4.39 | 4.39 |
| 299.17 | 4.50 | 4.50 |
| 234.30 | 4.04 | 4.04 |
| 250.30 | 3.74 | 3.74 |
| 245.28 | 3.60 | 3.60 |
| 265.27 | 3.64 | 3.64 |
| 278.31 | 3.52 | 3.52 |
| 264.28 | 3.43 | 3.43 |
| 254.72 | 4.39 | 4.39 |
| 299.17 | 4.50 | 4.50 |
| 234.30 | 4.04 | 4.04 |
| 250.30 | 3.74 | 3.74 |
| 236.27 | 3.44 | 3.44 |
| 278.31 | 3.52 | 3.52 |
| 238.26 | 3.87 | 3.87 |
| 254.72 | 4.39 | 4.39 |
| 299.17 | 4.50 | 4.50 |
| 234.30 | 4.04 | 4.04 |
| 250.30 | 3.74 | 3.74 |
| 238.26 | 3.87 | 3.87 |
| 157.22 | 3.20 | 3.20 |
| 237.28 | 4.48 | 4.48 |
| 287.34 | 5.63 | 5.63 |
| 255.27 | 4.62 | 4.62 |
| 271.72 | 5.13 | 5.13 |
| 316.17 | 5.24 | 5.24 |
| 267.30 | 4.49 | 4.49 |
| 262.29 | 4.35 | 4.35 |
| 282.27 | 4.39 | 4.39 |
| 168.20 | 2.70 | 2.70 |
| 168.20 | 2.70 | 2.70 |
| 186.19 | 2.84 | 2.84 |
| 211.23 | 1.85 | 1.85 |
| 229.22 | 1.99 | 1.99 |
| 219.22 | 2.49 | 2.49 |
| 205.19 | 2.40 | 2.40 |
| 191.21 | 2.31 | 2.31 |
| 262.29 | 4.37 | 4.37 |
| 258.25 | 2.78 | 2.78 |
| 230.20 | 2.30 | 2.30 |
| 249.20 | 1.86 | 1.86 |
| 222.29 | 3.35 | 3.35 |
| 218.26 | 2.96 | 2.96 |
| 236.32 | 3.74 | 3.74 |
| 156.19 | 2.23 | 2.23 |
| 170.21 | 2.62 | 2.62 |
| 185.19 | 1.35 | 1.35 |
| 199.22 | 1.27 | 1.27 |
| 213.24 | 1.47 | 1.47 |
| 242.35 | 3.83 | 3.83 |