Basic Information
ID: ALA1820080
Type: Binding
Description: Inhibition of squalene synthase in Wistar Charles River rat assessed as formation of squalene using [3H]FPP as substrate after 20 mins by scintillation counting
Format: BAO_0000357
Organism: Rattus norvegicus
Strain: Wistar Charles River
Target: Squalene synthetase(ALA3815)
Document: ALA1817583
Inhibition of squalene synthase in Wistar Charles River rat assessed as formation of squalene using [3H]FPP as substrate after 20 mins by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1820080
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 603.16 | 5.40 | 5.40 |
| 603.16 | 5.40 | 5.40 |
| 603.16 | 5.40 | 5.40 |
| 603.16 | 5.40 | 5.40 |
| 603.16 | 5.40 | 5.40 |
| 603.16 | 5.40 | 5.40 |
| 575.10 | 4.92 | 4.92 |
| 575.10 | 4.92 | 4.92 |
| 575.10 | 4.92 | 4.92 |
| 575.10 | 4.92 | 4.92 |
| 575.10 | 4.92 | 4.92 |
| 575.10 | 4.92 | 4.92 |
| 617.18 | 5.79 | 5.79 |
| 617.18 | 5.79 | 5.79 |
| 589.13 | 5.31 | 5.31 |
| 589.13 | 5.31 | 5.31 |
| 559.10 | 5.22 | 5.22 |
| 579.52 | 5.57 | 5.57 |
| 603.16 | 5.70 | 5.70 |
| 619.16 | 4.67 | 4.67 |
| 647.21 | 5.45 | 5.45 |
| 631.21 | 6.34 | 6.34 |
| 647.21 | 5.31 | 5.31 |