Basic Information
ID: ALA1821091
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1821091
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 450.92 | 2.26 | 2.26 |
| 464.94 | 2.65 | 2.65 |
| 476.95 | 2.82 | 2.82 |
| 478.97 | 3.04 | 3.04 |
| 493.00 | 3.43 | 3.43 |
| 507.02 | 3.82 | 3.82 |
| 448.94 | 2.81 | 2.81 |
| 462.97 | 3.21 | 3.21 |
| 477.00 | 3.60 | 3.60 |
| 491.02 | 3.99 | 3.99 |
| 481.01 | 3.36 | 3.36 |
| 495.04 | 3.75 | 3.75 |
| 492.95 | 2.41 | 2.41 |
| 506.98 | 2.80 | 2.80 |