Basic Information
ID: ALA1821160
Type: Binding
Description: Modulation of gamma-secretase expressed in CHO cells co-expressing human APP and wild type human presenilin-1 assessed as inhibition of amyloid beta42 production by ELISA
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1821160
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 206.28 | 3.07 | 3.07 |
| 273.72 | 4.16 | 4.16 |
| 466.60 | 5.46 | 5.46 |
| 602.60 | 7.49 | 7.49 |
| 478.70 | 6.91 | 6.91 |
| 446.59 | 6.36 | 6.36 |
| 444.57 | 6.59 | 6.59 |
| 464.63 | 6.67 | 6.67 |
| 448.56 | 5.95 | 5.95 |
| 446.59 | 6.36 | 6.36 |
| 446.59 | 6.36 | 6.36 |
| 446.59 | 6.36 | 6.36 |
| 444.57 | 6.59 | 6.59 |
| 456.67 | 8.04 | 8.04 |
| 580.57 | 8.63 | 8.63 |
| 552.51 | 8.54 | 8.54 |
| 504.59 | 8.29 | 8.29 |
| 458.68 | 7.82 | 7.82 |
| 452.64 | 7.09 | 7.09 |
| 452.64 | 7.09 | 7.09 |