Basic Information
ID: ALA1821169
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 mins
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1821169
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 376.41 | 0.46 | 0.46 |
| 448.47 | 1.65 | 1.65 |
| 344.41 | 1.12 | 1.12 |
| 358.43 | 1.43 | 1.43 |
| 372.46 | 1.68 | 1.68 |
| 386.49 | 2.07 | 2.07 |
| 386.49 | 2.24 | 2.24 |
| 384.47 | 2.00 | 2.00 |
| 370.45 | 1.76 | 1.76 |
| 374.43 | 1.13 | 1.13 |
| 388.46 | 1.52 | 1.52 |
| 390.50 | 1.84 | 1.84 |
| 360.41 | 0.83 | 0.83 |
| 362.40 | 1.26 | 1.26 |
| 378.85 | 1.77 | 1.77 |
| 412.40 | 2.14 | 2.14 |