Basic Information
ID: ALA1821390
Type: Binding
Description: Inhibition of Staphylococcus aureus DHFR assessed as oxidation of NADPH using dihydrofolate as substrate pre-incubated for 10 mins before substrate addition by spectrophotometry
Organism: Staphylococcus aureus
Activity Charts
Bioactivity
Activity Types for Assay ALA1821390
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 354.41 | 2.43 | 2.43 |
| 292.39 | 3.89 | 3.89 |
| 236.28 | 2.46 | 2.46 |
| 250.31 | 2.77 | 2.77 |
| 251.29 | 2.04 | 2.04 |
| 265.32 | 2.35 | 2.35 |
| 314.37 | 1.86 | 1.86 |
| 328.40 | 2.17 | 2.17 |
| 266.30 | 2.47 | 2.47 |
| 310.36 | 2.79 | 2.79 |
| 310.36 | 2.79 | 2.79 |
| 264.33 | 3.08 | 3.08 |
| 278.36 | 3.33 | 3.33 |
| 280.33 | 2.86 | 2.86 |
| 278.31 | 2.66 | 2.66 |
| 292.34 | 2.97 | 2.97 |
| 322.37 | 2.98 | 2.98 |
| 328.80 | 3.82 | 3.82 |
| 308.39 | 3.48 | 3.48 |
| 373.25 | 3.93 | 3.93 |
| 333.40 | 3.65 | 3.65 |
| 357.42 | 3.92 | 3.92 |
| 449.54 | 3.90 | 3.90 |
| 344.42 | 4.32 | 4.32 |
| 393.49 | 3.65 | 3.65 |