Assay Report Card

Basic Information

ID: ALA1821395

Type: Binding

Description: Inhibition of TMP-resistant Staphylococcus aureus DHFR F99Y mutant assessed as oxidation of NADPH using dihydrofolate as substrate pre-incubated for 10 mins before substrate addition by spectrophotometry

Organism: Staphylococcus aureus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
290.321.261.26
354.412.432.43
344.424.324.32
393.493.653.65