Basic Information
ID: ALA1825507
Type: Binding
Description: Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene assessed as HRE remaining activity at 10 uM preincubated for 1 hr under normoxia condition followed by 24 hrs incubation under hypoxia condition by alkaline phosphatase reporter assay relative to control
Organism: Homo sapiens
Cell type: LN229
Activity Charts
Bioactivity
Activity Types for Assay ALA1825507
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 335.41 | 4.23 | 4.23 |
| 333.39 | 3.67 | 3.67 |
| 312.41 | 4.32 | 4.32 |
| 284.36 | 3.69 | 3.69 |
| 465.57 | 5.28 | 5.28 |
| 518.46 | 6.58 | 6.58 |
| 463.60 | 5.58 | 5.58 |
| 440.39 | 5.78 | 5.78 |
| 416.50 | 4.38 | 4.38 |
| 341.48 | 4.98 | 4.98 |
| 495.60 | 5.29 | 5.29 |
| 504.44 | 6.58 | 6.58 |
| 474.41 | 6.57 | 6.57 |
| 385.53 | 4.78 | 4.78 |
| 368.86 | 5.49 | 5.49 |
| 448.36 | 6.48 | 6.48 |
| 449.57 | 5.58 | 5.58 |
| 405.52 | 5.79 | 5.79 |
| 494.57 | 5.18 | 5.18 |
| 478.39 | 6.49 | 6.49 |
| 414.34 | 5.68 | 5.68 |
| 431.55 | 4.49 | 4.49 |
| 419.55 | 5.78 | 5.78 |
| 509.62 | 5.29 | 5.29 |
| 480.54 | 5.18 | 5.18 |
| 305.38 | 4.22 | 4.22 |
| 375.49 | 5.78 | 5.78 |
| 367.45 | 5.25 | 5.25 |
| 254.33 | 3.68 | 3.68 |
| 400.91 | 6.51 | 6.51 |
| 363.46 | 4.87 | 4.87 |
| 347.42 | 3.59 | 3.59 |
| 316.40 | 4.71 | 4.71 |
| 233.27 | 2.69 | 2.69 |
| 313.40 | 3.30 | 3.30 |
| 203.24 | 2.68 | 2.68 |
| 307.39 | 4.42 | 4.42 |
| 351.45 | 4.43 | 4.43 |
| 204.27 | 2.92 | 2.92 |
| 386.45 | 2.98 | 2.98 |
| 186.25 | 3.51 | 3.51 |
| 391.52 | 4.47 | 4.47 |
| 292.38 | 3.95 | 3.95 |
| 273.38 | 3.63 | 3.63 |
| 337.42 | 4.43 | 4.43 |
| 463.45 | 3.10 | 3.10 |
| 445.48 | 3.73 | 3.73 |