Basic Information
ID: ALA1825508
Type: Binding
Description: Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene at 2.5 uM preincubated for 1 hr under normoxia condition followed by 24 hrs incubation under hypoxia condition by HRE-luciferase reporter assay relative to control
Organism: Homo sapiens
Cell type: LN229
Activity Charts
Bioactivity
Activity Types for Assay ALA1825508
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 591.09 | 7.62 | 7.62 |
| 465.57 | 5.28 | 5.28 |
| 474.41 | 6.57 | 6.57 |
| 582.44 | 6.92 | 6.92 |
| 469.61 | 6.42 | 6.42 |
| 484.02 | 5.92 | 5.92 |
| 488.44 | 6.57 | 6.57 |
| 464.54 | 5.17 | 5.17 |
| 479.60 | 5.28 | 5.28 |
| 479.60 | 5.28 | 5.28 |
| 577.06 | 7.62 | 7.62 |
| 568.41 | 6.93 | 6.93 |
| 455.58 | 6.42 | 6.42 |
| 469.99 | 5.93 | 5.93 |
| 450.52 | 5.17 | 5.17 |
| 465.57 | 5.28 | 5.28 |
| 583.11 | 7.75 | 7.75 |
| 574.46 | 7.06 | 7.06 |
| 461.63 | 6.55 | 6.55 |
| 476.04 | 6.06 | 6.06 |
| 480.46 | 6.70 | 6.70 |
| 456.56 | 5.30 | 5.30 |
| 471.62 | 5.41 | 5.41 |
| 471.62 | 5.41 | 5.41 |
| 557.07 | 7.07 | 7.07 |
| 548.42 | 6.38 | 6.38 |
| 435.59 | 5.87 | 5.87 |
| 450.00 | 5.38 | 5.38 |
| 454.42 | 6.02 | 6.02 |
| 430.53 | 4.63 | 4.63 |
| 445.58 | 4.73 | 4.73 |
| 445.58 | 4.73 | 4.73 |