Basic Information
ID: ALA1826381
Type: Binding
Description: Activation of SMN expressed in HEK293 cells assessed as concentration required to reach 50% of maximum luciferase signal by SMN2-promotor driven luciferase reporter gene assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1826381
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.31 | 3.04 | 3.04 |
| 330.46 | 2.58 | 2.58 |
| 323.26 | 4.56 | 4.56 |
| 363.49 | 4.18 | 4.18 |
| 366.28 | 3.27 | 3.27 |
| 337.45 | 3.67 | 3.67 |
| 329.43 | 2.71 | 2.71 |
| 355.42 | 2.62 | 2.62 |
| 301.42 | 2.82 | 2.82 |
| 366.28 | 3.27 | 3.27 |
| 305.38 | 2.65 | 2.65 |
| 345.42 | 2.28 | 2.28 |
| 306.39 | 2.12 | 2.12 |
| 317.41 | 2.52 | 2.52 |
| 293.42 | 2.57 | 2.57 |
| 327.41 | 3.26 | 3.26 |
| 325.23 | 3.41 | 3.41 |
| 330.46 | 2.58 | 2.58 |
| 305.38 | 2.65 | 2.65 |
| 340.45 | 3.00 | 3.00 |
| 329.43 | 2.71 | 2.71 |
| 288.38 | 1.91 | 1.91 |
| 321.83 | 3.17 | 3.17 |
| 365.48 | 1.92 | 1.92 |
| 355.39 | 3.53 | 3.53 |
| 470.44 | 5.15 | 5.15 |
| 464.41 | 4.08 | 4.08 |
| 347.44 | 2.53 | 2.53 |
| 393.51 | 4.09 | 4.09 |
| 367.27 | 3.87 | 3.87 |
| 358.46 | 3.78 | 3.78 |
| 418.32 | 4.13 | 4.13 |
| 442.38 | 5.43 | 5.43 |
| 388.49 | 3.75 | 3.75 |
| 380.31 | 3.68 | 3.68 |
| 382.49 | 4.08 | 4.08 |
| 312.40 | 2.38 | 2.38 |
| 361.24 | 2.61 | 2.61 |
| 363.49 | 4.18 | 4.18 |
| 343.41 | 2.05 | 2.05 |
| 343.50 | 3.81 | 3.81 |
| 360.44 | 2.07 | 2.07 |
| 355.39 | 3.53 | 3.53 |
| 345.42 | 2.28 | 2.28 |
| 325.42 | 1.91 | 1.91 |
| 498.49 | 5.93 | 5.93 |
| 305.38 | 2.65 | 2.65 |
| 395.32 | 4.35 | 4.35 |
| 321.83 | 3.17 | 3.17 |
| 394.34 | 3.88 | 3.88 |
| 331.40 | 2.24 | 2.24 |
| 435.55 | 4.83 | 4.83 |
| 331.45 | 1.97 | 1.97 |
| 371.51 | 2.90 | 2.90 |
| 377.47 | 2.54 | 2.54 |
| 428.36 | 4.54 | 4.54 |
| 333.48 | 3.23 | 3.23 |
| 331.44 | 2.91 | 2.91 |
| 345.47 | 3.30 | 3.30 |
| 332.39 | 2.42 | 2.42 |
| 356.50 | 3.11 | 3.11 |
| 367.27 | 2.67 | 2.67 |
| 325.42 | 1.91 | 1.91 |
| 391.30 | 3.47 | 3.47 |
| 325.42 | 1.91 | 1.91 |
| 332.39 | 2.42 | 2.42 |
| 321.83 | 3.17 | 3.17 |
| 312.40 | 2.38 | 2.38 |
| 370.52 | 3.50 | 3.50 |
| 347.44 | 2.53 | 2.53 |
| 355.39 | 3.53 | 3.53 |
| 435.39 | 3.22 | 3.22 |
| 484.46 | 5.54 | 5.54 |
| 344.44 | 2.47 | 2.47 |
| 372.49 | 2.35 | 2.35 |
| 302.40 | 2.22 | 2.22 |
| 324.25 | 2.98 | 2.98 |
| 379.49 | 4.30 | 4.30 |
| 393.54 | 4.88 | 4.88 |
| 337.45 | 3.67 | 3.67 |
| 345.47 | 3.30 | 3.30 |
| 359.50 | 3.55 | 3.55 |
| 348.27 | 4.31 | 4.31 |
| 366.28 | 3.27 | 3.27 |
| 340.38 | 1.62 | 1.62 |
| 340.43 | 2.63 | 2.63 |
| 359.45 | 2.67 | 2.67 |
| 380.31 | 3.54 | 3.54 |
| 296.37 | 2.15 | 2.15 |
| 371.38 | 3.41 | 3.41 |
| 354.41 | 2.01 | 2.01 |
| 436.38 | 3.65 | 3.65 |
| 287.39 | 2.51 | 2.51 |
| 330.46 | 2.58 | 2.58 |
| 354.41 | 2.01 | 2.01 |
| 367.27 | 2.77 | 2.77 |
| 301.42 | 2.82 | 2.82 |
| 367.38 | 2.83 | 2.83 |
| 302.40 | 2.09 | 2.09 |
| 301.42 | 2.82 | 2.82 |
| 366.28 | 3.27 | 3.27 |
| 317.41 | 2.52 | 2.52 |
| 326.40 | 1.31 | 1.31 |
| 456.41 | 5.11 | 5.11 |
| 338.27 | 3.50 | 3.50 |
| 355.40 | 1.40 | 1.40 |
| 305.38 | 2.65 | 2.65 |
| 366.28 | 3.24 | 3.24 |
| 345.47 | 3.30 | 3.30 |
| 330.46 | 2.58 | 2.58 |
| 347.44 | 2.53 | 2.53 |
| 360.44 | 3.27 | 3.27 |
| 302.40 | 2.09 | 2.09 |
| 343.41 | 2.05 | 2.05 |
| 353.50 | 3.98 | 3.98 |
| 329.47 | 3.68 | 3.68 |
| 321.83 | 3.17 | 3.17 |
| 359.45 | 2.67 | 2.67 |
| 331.40 | 2.24 | 2.24 |
| 332.39 | 2.42 | 2.42 |
| 325.42 | 1.91 | 1.91 |
| 365.48 | 1.92 | 1.92 |
| 317.41 | 2.52 | 2.52 |
| 365.48 | 1.92 | 1.92 |
| 358.47 | 2.21 | 2.21 |
| 312.40 | 2.38 | 2.38 |
| 329.43 | 2.45 | 2.45 |
| 438.39 | 5.07 | 5.07 |
| 402.34 | 2.65 | 2.65 |
| 285.15 | 0.94 | 0.94 |
| 240.69 | 0.83 | 0.83 |
| 339.44 | 2.22 | 2.22 |
| 290.19 | 1.61 | 1.61 |