Basic Information
ID: ALA1826482
Type: Binding
Description: Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA method
Organism: Homo sapiens
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA1826482
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 641.62 | 6.11 | 6.11 |
| 450.35 | 5.04 | 5.04 |
| 525.48 | 5.92 | 5.92 |
| 456.59 | 4.61 | 4.61 |
| 474.58 | 4.75 | 4.75 |
| 491.04 | 5.26 | 5.26 |
| 481.60 | 4.48 | 4.48 |
| 524.59 | 5.63 | 5.63 |
| 512.70 | 5.91 | 5.91 |
| 525.48 | 5.92 | 5.92 |
| 509.03 | 5.40 | 5.40 |
| 527.02 | 5.54 | 5.54 |
| 541.04 | 6.10 | 6.10 |
| 539.51 | 6.48 | 6.48 |
| 557.50 | 6.62 | 6.62 |
| 301.15 | 4.25 | 4.25 |
| 380.04 | 5.01 | 5.01 |
| 326.16 | 4.12 | 4.12 |
| 420.27 | 5.50 | 5.50 |
| 377.25 | 5.92 | 5.92 |
| 557.50 | 6.62 | 6.62 |
| 517.43 | 5.74 | 5.74 |
| 517.43 | 5.74 | 5.74 |
| 367.21 | 4.44 | 4.44 |
| 381.24 | 4.65 | 4.65 |
| 384.26 | 5.37 | 5.37 |
| 368.20 | 4.90 | 4.90 |
| 367.21 | 4.64 | 4.64 |
| 367.21 | 4.64 | 4.64 |
| 395.27 | 5.26 | 5.26 |
| 381.24 | 4.65 | 4.65 |
| 409.29 | 5.69 | 5.69 |
| 523.44 | 4.53 | 4.53 |
| 509.41 | 4.18 | 4.18 |
| 481.36 | 4.65 | 4.65 |
| 436.32 | 4.33 | 4.33 |
| 493.37 | 3.53 | 3.53 |
| 422.29 | 4.26 | 4.26 |
| 436.32 | 4.65 | 4.65 |
| 450.35 | 5.04 | 5.04 |
| 451.33 | 5.46 | 5.46 |
| 450.35 | 5.04 | 5.04 |