Basic Information
ID: ALA1827309
Type: Binding
Description: Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1827309
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.39 | 3.86 | 3.86 |
| 449.41 | 4.33 | 4.33 |
| 445.44 | 4.50 | 4.50 |
| 447.48 | 4.90 | 4.90 |
| 449.41 | 4.33 | 4.33 |
| 445.44 | 4.50 | 4.50 |
| 447.48 | 4.90 | 4.90 |
| 449.41 | 4.33 | 4.33 |
| 510.31 | 4.95 | 4.95 |
| 510.31 | 4.95 | 4.95 |
| 419.38 | 4.32 | 4.32 |
| 493.46 | 4.54 | 4.54 |
| 461.44 | 4.20 | 4.20 |
| 449.41 | 4.33 | 4.33 |
| 461.44 | 4.20 | 4.20 |
| 493.46 | 4.54 | 4.54 |
| 461.44 | 4.20 | 4.20 |
| 505.50 | 4.22 | 4.22 |
| 399.40 | 3.85 | 3.85 |