Basic Information
ID: ALA1827521
Type: Binding
Description: Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis
Cell type: COS-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1827521
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.47 | 3.69 | 3.69 |
| 429.48 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 433.90 | 5.35 | 5.35 |
| 447.93 | 5.60 | 5.60 |
| 447.93 | 5.74 | 5.74 |
| 447.93 | 5.74 | 5.74 |
| 447.93 | 5.52 | 5.52 |
| 449.90 | 4.45 | 4.45 |
| 451.89 | 5.43 | 5.43 |
| 434.89 | 4.29 | 4.29 |
| 378.43 | 4.16 | 4.16 |
| 392.46 | 4.47 | 4.47 |
| 379.42 | 3.55 | 3.55 |
| 379.42 | 3.55 | 3.55 |
| 379.42 | 3.55 | 3.55 |
| 380.41 | 2.95 | 2.95 |
| 380.41 | 2.95 | 2.95 |
| 428.49 | 5.31 | 5.31 |
| 429.48 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 382.85 | 4.80 | 4.80 |
| 383.84 | 4.20 | 4.20 |
| 383.84 | 4.20 | 4.20 |
| 384.83 | 3.59 | 3.59 |
| 384.83 | 3.59 | 3.59 |
| 433.90 | 5.35 | 5.35 |
| 433.90 | 5.35 | 5.35 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 436.90 | 4.69 | 4.69 |
| 418.54 | 5.35 | 5.35 |
| 376.50 | 5.04 | 5.04 |
| 404.90 | 5.32 | 5.32 |
| 418.88 | 4.96 | 4.96 |
| 430.46 | 4.67 | 4.67 |
| 414.47 | 4.80 | 4.80 |
| 351.41 | 3.19 | 3.19 |
| 399.45 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 429.48 | 4.70 | 4.70 |
| 443.51 | 4.73 | 4.73 |
| 413.48 | 5.00 | 5.00 |
| 439.52 | 5.04 | 5.04 |
| 433.90 | 5.35 | 5.35 |
| 467.45 | 5.72 | 5.72 |
| 441.54 | 5.82 | 5.82 |
| 424.46 | 4.57 | 4.57 |
| 450.50 | 5.24 | 5.24 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 434.89 | 4.74 | 4.74 |
| 418.46 | 4.30 | 4.30 |
| 391.48 | 3.97 | 3.97 |
| 391.48 | 4.12 | 4.12 |
| 405.50 | 4.51 | 4.51 |
| 406.49 | 4.93 | 4.93 |
| 511.99 | 4.75 | 4.75 |
| 511.99 | 4.75 | 4.75 |
| 458.91 | 5.22 | 5.22 |
| 458.91 | 5.22 | 5.22 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 421.50 | 3.48 | 3.48 |
| 407.47 | 3.35 | 3.35 |
| 406.49 | 2.93 | 2.93 |
| 420.52 | 3.27 | 3.27 |
| 448.53 | 3.18 | 3.18 |
| 439.54 | 3.08 | 3.08 |
| 455.54 | 2.75 | 2.75 |
| 441.48 | 4.75 | 4.75 |
| 408.51 | 3.85 | 3.85 |
| 458.54 | 2.09 | 2.09 |
| 409.49 | 2.79 | 2.79 |
| 445.47 | 3.03 | 3.03 |
| 406.49 | 3.45 | 3.45 |