Basic Information
ID: ALA1827704
Type: Binding
Description: Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric analysis
Cell type: COS-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1827704
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.47 | 3.69 | 3.69 |
| 433.90 | 5.35 | 5.35 |
| 434.89 | 4.29 | 4.29 |
| 436.90 | 4.69 | 4.69 |
| 405.50 | 4.51 | 4.51 |
| 511.99 | 4.75 | 4.75 |
| 511.99 | 4.75 | 4.75 |
| 458.91 | 5.22 | 5.22 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 463.93 | 5.36 | 5.36 |
| 407.47 | 3.35 | 3.35 |
| 406.49 | 2.93 | 2.93 |
| 448.53 | 3.18 | 3.18 |
| 439.54 | 3.08 | 3.08 |
| 455.54 | 2.75 | 2.75 |
| 441.48 | 4.75 | 4.75 |
| 408.51 | 3.85 | 3.85 |
| 458.54 | 2.09 | 2.09 |
| 409.49 | 2.79 | 2.79 |
| 445.47 | 3.03 | 3.03 |
| 406.49 | 3.45 | 3.45 |