Basic Information
ID: ALA1828129
Type: Binding
Description: Inhibition of recombinant human TOP1 mediated DNA cleavage after 20 mins by gel electrophoresis relative to camptothecin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1828129
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 365.34 | 2.50 | 2.50 |
| 452.46 | 1.93 | 1.93 |
| 478.50 | 2.68 | 2.68 |
| 459.46 | 3.25 | 3.25 |
| 321.33 | 1.57 | 1.57 |
| 321.33 | 1.57 | 1.57 |
| 321.33 | 1.57 | 1.57 |
| 381.38 | 0.29 | 0.29 |
| 381.38 | 0.29 | 0.29 |
| 411.41 | -0.35 | -0.35 |
| 381.38 | 0.29 | 0.29 |
| 381.38 | 0.29 | 0.29 |
| 411.41 | -0.35 | -0.35 |
| 411.41 | -0.35 | -0.35 |
| 456.41 | -0.44 | -0.44 |
| 305.33 | 2.77 | 2.77 |
| 305.33 | 2.77 | 2.77 |
| 305.33 | 2.77 | 2.77 |
| 319.32 | 1.77 | 1.77 |
| 305.33 | 2.59 | 2.59 |
| 305.33 | 2.59 | 2.59 |
| 305.33 | 2.59 | 2.59 |
| 320.35 | 1.53 | 1.53 |
| 381.38 | 1.58 | 1.58 |
| 366.33 | 1.47 | 1.47 |