Basic Information
ID: ALA1831610
Type: Binding
Description: Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX at 100 nM after 16 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Cell type: HEK293
Target: TGF-beta receptor type I(ALA4439)
Document: ALA1828567
Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX at 100 nM after 16 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1831610
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.49 | 4.11 | 4.11 |
| 385.47 | 4.14 | 4.14 |
| 298.35 | 4.20 | 4.20 |
| 288.31 | 2.72 | 2.72 |
| 288.31 | 2.72 | 2.72 |
| 338.37 | 3.87 | 3.87 |
| 305.39 | 3.52 | 3.52 |
| 320.40 | 2.29 | 2.29 |
| 222.25 | 2.53 | 2.53 |
| 400.49 | 3.93 | 3.93 |
| 397.49 | 3.35 | 3.35 |
| 299.34 | 3.60 | 3.60 |
| 299.34 | 3.60 | 3.60 |
| 349.40 | 4.75 | 4.75 |
| 349.40 | 4.75 | 4.75 |
| 300.33 | 2.99 | 2.99 |
| 302.34 | 2.93 | 2.93 |