Basic Information
ID: ALA1831796
Type: Binding
Description: Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol after 1 hr by scintillation proximity assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1831796
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.36 | 4.26 | 4.26 |
| 267.33 | 4.08 | 4.08 |
| 267.33 | 4.08 | 4.08 |
| 267.33 | 3.95 | 3.95 |
| 301.77 | 4.60 | 4.60 |
| 301.77 | 4.60 | 4.60 |
| 346.22 | 4.71 | 4.71 |
| 301.77 | 4.60 | 4.60 |
| 335.32 | 4.97 | 4.97 |
| 360.25 | 4.71 | 4.71 |
| 343.43 | 5.62 | 5.62 |
| 361.42 | 5.75 | 5.75 |
| 361.42 | 5.75 | 5.75 |
| 361.42 | 5.75 | 5.75 |
| 379.41 | 5.89 | 5.89 |
| 405.44 | 6.45 | 6.45 |
| 409.43 | 5.26 | 5.26 |
| 423.46 | 5.65 | 5.65 |
| 437.49 | 5.81 | 5.81 |
| 451.51 | 6.20 | 6.20 |
| 419.50 | 5.67 | 5.67 |
| 433.52 | 6.06 | 6.06 |
| 447.55 | 6.45 | 6.45 |
| 455.48 | 5.95 | 5.95 |
| 469.50 | 6.34 | 6.34 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 437.49 | 5.81 | 5.81 |
| 468.48 | 5.45 | 5.45 |
| 454.49 | 5.92 | 5.92 |
| 496.53 | 6.10 | 6.10 |
| 497.52 | 5.63 | 5.63 |
| 511.54 | 5.89 | 5.89 |
| 525.57 | 6.28 | 6.28 |
| 532.58 | 5.51 | 5.51 |
| 533.57 | 4.75 | 4.75 |
| 482.50 | 5.84 | 5.84 |
| 496.53 | 6.10 | 6.10 |
| 468.52 | 6.31 | 6.31 |
| 511.54 | 6.02 | 6.02 |
| 525.57 | 6.28 | 6.28 |
| 546.61 | 5.90 | 5.90 |
| 455.48 | 5.95 | 5.95 |
| 455.48 | 5.95 | 5.95 |
| 455.48 | 5.95 | 5.95 |