Basic Information
ID: ALA1831798
Type: Binding
Description: Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]-cortisone to [3H]-cortisol after 1 hr by scintillation proximity assay in presence of human plasma
Organism: Homo sapiens
Tissue: Plasma
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA1831798
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.49 | 5.81 | 5.81 |
| 451.51 | 6.20 | 6.20 |
| 419.50 | 5.67 | 5.67 |
| 433.52 | 6.06 | 6.06 |
| 447.55 | 6.45 | 6.45 |
| 455.48 | 5.95 | 5.95 |
| 469.50 | 6.34 | 6.34 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 437.49 | 5.81 | 5.81 |
| 468.48 | 5.45 | 5.45 |
| 496.53 | 6.10 | 6.10 |
| 497.52 | 5.63 | 5.63 |
| 532.58 | 5.51 | 5.51 |
| 533.57 | 4.75 | 4.75 |
| 482.50 | 5.84 | 5.84 |
| 511.54 | 6.02 | 6.02 |
| 546.61 | 5.90 | 5.90 |