Basic Information
ID: ALA1831799
Type: ADME
Description: Inhibition of human CYP3A4 assessed as rate of [14C]-formaldehyde/formic acid production by liquid scintillation counting
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1831799
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.51 | 6.20 | 6.20 |
| 433.52 | 6.06 | 6.06 |
| 447.55 | 6.45 | 6.45 |
| 455.48 | 5.95 | 5.95 |
| 469.50 | 6.34 | 6.34 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 451.51 | 6.20 | 6.20 |
| 437.49 | 5.81 | 5.81 |
| 468.48 | 5.45 | 5.45 |
| 454.49 | 5.92 | 5.92 |
| 497.52 | 5.63 | 5.63 |
| 511.54 | 5.89 | 5.89 |
| 532.58 | 5.51 | 5.51 |
| 533.57 | 4.75 | 4.75 |
| 482.50 | 5.84 | 5.84 |
| 468.52 | 6.31 | 6.31 |
| 511.54 | 6.02 | 6.02 |
| 525.57 | 6.28 | 6.28 |
| 546.61 | 5.90 | 5.90 |