Basic Information
ID: ALA1832641
Type: Functional
Description: Inhibition of human wild-type CFTR expressed in FRT cells coexpressing YFP-H148Q assessed as inhibition of cAMP agonist-induced iodide influx after 45 mins by fluorescence plate-reader analysis
Organism: Homo sapiens
Cell type: FRT
Activity Charts
Bioactivity
Activity Types for Assay ALA1832641
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.49 | 4.11 | 4.11 |
| 516.58 | 3.47 | 3.47 |
| 514.97 | 4.27 | 4.27 |
| 480.52 | 4.05 | 4.05 |
| 467.49 | 4.19 | 4.19 |
| 452.51 | 4.14 | 4.14 |
| 452.51 | 4.37 | 4.37 |
| 454.56 | 4.58 | 4.58 |
| 452.51 | 4.42 | 4.42 |
| 458.91 | 4.46 | 4.46 |
| 503.36 | 4.57 | 4.57 |
| 550.36 | 4.41 | 4.41 |
| 492.46 | 4.82 | 4.82 |
| 500.56 | 5.47 | 5.47 |
| 454.49 | 3.30 | 3.30 |
| 474.52 | 4.96 | 4.96 |
| 504.34 | 4.53 | 4.53 |
| 551.34 | 4.37 | 4.37 |
| 439.47 | 4.08 | 4.08 |
| 473.92 | 4.73 | 4.73 |
| 453.50 | 4.39 | 4.39 |
| 549.34 | 4.44 | 4.44 |
| 484.47 | 3.99 | 3.99 |
| 548.35 | 4.47 | 4.47 |
| 518.91 | 4.64 | 4.64 |
| 576.40 | 4.71 | 4.71 |
| 511.53 | 4.25 | 4.25 |
| 548.35 | 4.23 | 4.23 |