Basic Information
ID: ALA1833626
Type: Functional
Description: Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as inhibition of CRF-induced cAMP accumulation after 15 mins by cAMP enzyme immunoassay
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA1833626
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 359.86 | 4.74 | 4.74 |
| 373.89 | 5.04 | 5.04 |
| 373.89 | 4.76 | 4.76 |
| 387.92 | 5.07 | 5.07 |
| 401.94 | 5.32 | 5.32 |
| 415.97 | 5.71 | 5.71 |
| 415.97 | 5.88 | 5.88 |
| 430.00 | 6.10 | 6.10 |
| 442.01 | 6.42 | 6.42 |
| 403.91 | 4.77 | 4.77 |
| 387.92 | 4.79 | 4.79 |
| 401.94 | 5.18 | 5.18 |
| 415.97 | 5.57 | 5.57 |
| 427.98 | 5.73 | 5.73 |
| 413.95 | 5.34 | 5.34 |
| 427.98 | 5.57 | 5.57 |
| 431.97 | 4.80 | 4.80 |
| 417.94 | 4.76 | 4.76 |
| 374.88 | 4.44 | 4.44 |
| 374.88 | 4.15 | 4.15 |
| 388.90 | 4.46 | 4.46 |
| 388.90 | 4.18 | 4.18 |
| 387.92 | 5.07 | 5.07 |
| 387.92 | 4.79 | 4.79 |
| 401.94 | 5.18 | 5.18 |
| 388.90 | 4.18 | 4.18 |
| 383.88 | 5.45 | 5.45 |
| 377.49 | 5.36 | 5.36 |
| 381.91 | 6.00 | 6.00 |
| 360.51 | 5.56 | 5.56 |
| 361.49 | 5.71 | 5.71 |
| 378.48 | 5.41 | 5.41 |