Basic Information
ID: ALA1837249
Type: Binding
Description: Inhibition of human recombinant cathepsin L expressed in Escherichia coli assessed as formation of fluorescent degradation product AMC using Z-Phe-Arg-AMC as substrate at 50 uM by fluorescence microplate assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Cathepsin L(ALA3837)
Document: ALA1833856
Inhibition of human recombinant cathepsin L expressed in Escherichia coli assessed as formation of fluorescent degradation product AMC using Z-Phe-Arg-AMC as substrate at 50 uM by fluorescence microplate assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1837249
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.49 | 3.76 | 3.76 |
| 371.49 | 3.76 | 3.76 |
| 371.49 | 3.76 | 3.76 |
| 359.45 | 3.89 | 3.89 |
| 359.45 | 3.89 | 3.89 |
| 359.45 | 3.89 | 3.89 |
| 386.46 | 3.66 | 3.66 |
| 386.46 | 3.66 | 3.66 |
| 386.46 | 3.66 | 3.66 |
| 375.91 | 4.40 | 4.40 |
| 375.91 | 4.40 | 4.40 |
| 375.91 | 4.40 | 4.40 |
| 366.47 | 3.62 | 3.62 |
| 366.47 | 3.62 | 3.62 |
| 366.47 | 3.62 | 3.62 |
| 384.46 | 3.76 | 3.76 |
| 279.39 | 2.57 | 2.57 |
| 293.42 | 2.96 | 2.96 |
| 307.44 | 3.35 | 3.35 |
| 290.37 | 2.07 | 2.07 |
| 309.37 | 1.63 | 1.63 |
| 305.43 | 2.96 | 2.96 |
| 319.46 | 3.35 | 3.35 |
| 333.48 | 3.74 | 3.74 |
| 347.51 | 4.13 | 4.13 |
| 293.30 | 1.74 | 1.74 |
| 276.25 | 1.33 | 1.33 |
| 286.24 | -0.38 | -0.38 |
| 454.51 | 2.90 | 2.90 |
| 291.26 | 1.47 | 1.47 |
| 302.14 | 3.03 | 3.03 |
| 299.12 | 2.71 | 2.71 |
| 329.19 | 2.85 | 2.85 |
| 297.19 | 4.22 | 4.22 |
| 269.14 | 3.48 | 3.48 |
| 285.13 | 2.46 | 2.46 |
| 319.98 | 3.68 | 3.68 |
| 356.17 | 2.12 | 2.12 |
| 398.25 | 2.99 | 2.99 |
| 285.13 | 2.80 | 2.80 |
| 335.80 | 1.64 | 1.64 |
| 323.78 | 1.23 | 1.23 |
| 323.78 | 1.57 | 1.57 |
| 205.24 | 1.12 | 1.12 |
| 250.24 | 1.03 | 1.03 |
| 219.27 | 1.43 | 1.43 |
| 251.34 | 1.75 | 1.75 |