Basic Information
ID: ALA1837504
Type: Binding
Description: Selectivity ratio of IC50 for gamma-secretase-mediated Notch cleavage in human SNC-204B8 cells to IC50 for gamma-secretase-mediated amyloid precursor protein-cleavage in human IMR32 cells
Organism: Homo sapiens
Cell type: IMR-32
Activity Charts
Bioactivity
Activity Types for Assay ALA1837504
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.83 | 2.90 | 2.90 |
| 447.48 | 4.66 | 4.66 |
| 448.47 | 4.06 | 4.06 |
| 419.96 | 4.36 | 4.36 |
| 447.48 | 4.66 | 4.66 |
| 447.48 | 4.66 | 4.66 |
| 466.46 | 4.20 | 4.20 |
| 466.46 | 4.20 | 4.20 |
| 466.46 | 4.20 | 4.20 |
| 532.54 | 4.62 | 4.62 |
| 513.55 | 4.85 | 4.85 |
| 530.60 | 5.79 | 5.79 |
| 504.53 | 4.62 | 4.62 |
| 453.96 | 4.17 | 4.17 |
| 448.47 | 4.06 | 4.06 |
| 453.45 | 3.35 | 3.35 |
| 469.51 | 3.82 | 3.82 |
| 435.96 | 3.46 | 3.46 |
| 419.89 | 2.99 | 2.99 |
| 523.48 | 4.53 | 4.53 |
| 421.94 | 3.15 | 3.15 |
| 438.44 | 2.78 | 2.78 |