Basic Information
ID: ALA1837593
Type: Binding
Description: Inhibition of recombinant trypanothione reductase from Trypanosoma brucei brucei S427 by DTNB-coupled spectrophotometric assay
Organism: Trypanosoma brucei brucei
Strain: S427
Activity Charts
Bioactivity
Activity Types for Assay ALA1837593
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 387.28 | 4.47 | 4.47 |
| 359.22 | 3.99 | 3.99 |
| 373.25 | 2.89 | 2.89 |
| 458.36 | 3.39 | 3.39 |
| 308.38 | 3.62 | 3.62 |
| 472.38 | 3.78 | 3.78 |
| 370.45 | 4.65 | 4.65 |
| 460.53 | 4.68 | 4.68 |
| 346.86 | 6.00 | 6.00 |
| 360.89 | 6.04 | 6.04 |
| 376.89 | 6.00 | 6.00 |
| 364.85 | 6.13 | 6.13 |
| 381.31 | 6.65 | 6.65 |
| 414.86 | 7.01 | 7.01 |
| 389.93 | 6.06 | 6.06 |
| 360.89 | 6.30 | 6.30 |
| 381.31 | 6.65 | 6.65 |
| 414.86 | 7.01 | 7.01 |
| 284.79 | 4.81 | 4.81 |
| 367.92 | 5.28 | 5.28 |
| 369.90 | 4.13 | 4.13 |
| 382.94 | 4.04 | 4.04 |
| 327.86 | 4.36 | 4.36 |
| 341.89 | 4.75 | 4.75 |
| 313.83 | 4.01 | 4.01 |
| 300.79 | 3.79 | 3.79 |
| 399.92 | 5.32 | 5.32 |
| 341.84 | 3.93 | 3.93 |
| 367.88 | 4.32 | 4.32 |
| 356.22 | 3.01 | 3.01 |
| 370.25 | 3.40 | 3.40 |
| 373.25 | 4.08 | 4.08 |
| 328.80 | 3.97 | 3.97 |
| 407.70 | 4.73 | 4.73 |
| 387.28 | 4.47 | 4.47 |
| 403.91 | 5.22 | 5.22 |
| 393.87 | 4.82 | 4.82 |
| 417.94 | 5.15 | 5.15 |
| 371.87 | 3.56 | 3.56 |
| 384.91 | 3.47 | 3.47 |
| 469.03 | 5.35 | 5.35 |
| 410.95 | 3.96 | 3.96 |
| 436.99 | 4.35 | 4.35 |
| 473.02 | 5.25 | 5.25 |
| 462.98 | 4.85 | 4.85 |
| 487.05 | 5.18 | 5.18 |
| 440.98 | 3.59 | 3.59 |
| 454.02 | 3.50 | 3.50 |
| 333.48 | 4.63 | 4.63 |
| 412.38 | 5.39 | 5.39 |
| 399.54 | 5.89 | 5.89 |
| 459.38 | 5.23 | 5.23 |
| 409.58 | 6.29 | 6.29 |
| 410.57 | 5.69 | 5.69 |
| 415.61 | 6.36 | 6.36 |
| 459.64 | 7.45 | 7.45 |
| 449.60 | 7.04 | 7.04 |
| 420.78 | 5.51 | 5.51 |
| 417.98 | 6.41 | 6.41 |
| 355.91 | 5.06 | 5.06 |
| 436.81 | 6.59 | 6.59 |
| 424.03 | 6.58 | 6.58 |
| 385.91 | 5.42 | 5.42 |
| 397.95 | 5.29 | 5.29 |
| 373.97 | 5.81 | 5.81 |
| 401.91 | 4.52 | 4.52 |
| 413.95 | 4.39 | 4.39 |
| 397.95 | 4.69 | 4.69 |
| 402.37 | 5.93 | 5.93 |
| 385.91 | 5.42 | 5.42 |
| 397.95 | 5.29 | 5.29 |
| 381.95 | 5.59 | 5.59 |
| 402.37 | 5.93 | 5.93 |
| 381.95 | 5.59 | 5.59 |
| 395.98 | 5.90 | 5.90 |
| 381.95 | 5.48 | 5.48 |
| 383.92 | 4.99 | 4.99 |
| 383.92 | 4.99 | 4.99 |